Description

n-Methyl-n-(4-Nitrophenyl)-2-(Piperazin-1-Yl)Acetamide is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex biological pathways. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need this material for drug discovery programs, process development, and the production of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block in multi-step synthetic routes for target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Reference Standard: High-purity grades are suitable for use as an analytical standard in quality control laboratories.

Basic Information

Product Name	n-Methyl-n-(4-Nitrophenyl)-2-(Piperazin-1-Yl)Acetamide
CAS No.	2037385-84-3
Molecular Formula	C14H20N4O3
Molecular Weight	292.34 g/mol
Synonyms	N-Methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide; 2-(Piperazin-1-yl)-N-methyl-N-(4-nitrophenyl)acetamide; 1-[2-[(4-Nitrophenyl)(methyl)amino]-2-oxoethyl]piperazine; Acetamide, N-methyl-N-(4-nitrophenyl)-2-(1-piperazinyl)-; UNII-8V6F2Q8Q2F; 2037385-84-3; CHEMBL3186472
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(4-Nitrophenyl)-2-(Piperazin-1-Yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.