Description

1-((2R,4R)-2-(1H-Benzo[D]Imidazol-2-Yl)-1-Methylpiperidin-4-Yl)-3-(4-Cyanophenyl)Urea Maleate is a high-purity, non-racemic chiral compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical building block or potential active pharmaceutical ingredient (API) intermediate for targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) or oncology targets.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and receptor binding studies to investigate mechanism of action.
• Preclinical Development: Employed in the formulation of test articles for pharmacokinetic, pharmacodynamic, and toxicology studies in animal models.
• Process Chemistry: Acts as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies and the generation of analog libraries for lead optimization.

Basic Information

Product Name	1-((2R,4R)-2-(1H-Benzo[D]Imidazol-2-Yl)-1-Methylpiperidin-4-Yl)-3-(4-Cyanophenyl)Urea Maleate
CAS No.	2030410-25-2
Molecular Formula	C26H27N7O5
Molecular Weight	517.54 g/mol
Synonyms	1-[(2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methyl-4-piperidinyl]-3-(4-cyanophenyl)urea maleate; (2R,4R)-2-(1H-Benzoimidazol-2-yl)-1-methyl-4-[3-(4-cyanophenyl)ureido]piperidine maleate; UNII-7V9B8D4I0R; 7V9B8D4I0R; 1-((2R,4R)-2-(1H-Benzoimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate; 1-[(2R,4R)-2-(1H-1,3-Benzodiazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea (Z)-but-2-enedioate
EINECS	Contact for details

Quality Control

Our 1-((2R,4R)-2-(1H-Benzo[D]Imidazol-2-Yl)-1-Methylpiperidin-4-Yl)-3-(4-Cyanophenyl)Urea Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.