Description

1-(3,3-Difluorocyclobutyl)Piperazine (Wxc08972) is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutyl scaffold with fluorine substitution. This compound is of significant value for medicinal chemistry research and development, offering a versatile building block for creating novel bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in therapeutic areas like central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs) targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to modulate pharmacokinetic properties like metabolic stability and membrane permeability.
• Ligand Synthesis: Serves as a precursor for constructing complex ligands in catalyst systems or diagnostic imaging agents.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for investigating biological pathways and target validation.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with enhanced efficacy.
• Material Science: Can be utilized in the synthesis of specialty polymers or advanced organic frameworks.

Basic Information

Item	Details
Product Name	1-(3,3-Difluorocyclobutyl)Piperazine (Wxc08972)
CAS No.	2020056-51-1
Molecular Formula	C8H14F2N2
Molecular Weight	176.21 g/mol
Synonyms	1-(3,3-Difluorocyclobutyl)piperazine; 3,3-Difluorocyclobutylpiperazine; WXC-08972; Wxc08972; Piperazine, 1-(3,3-difluorocyclobutyl)-; 2020056-51-1; (3,3-Difluorocyclobutyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(3,3-Difluorocyclobutyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.