Description

(S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride is a high-purity chiral piperazinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex, biologically active molecules with precise stereochemistry, which is essential for modern drug discovery and development. This compound is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating novel therapeutics, particularly in areas like central nervous system (CNS) agents and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Asymmetric Synthesis: Used in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	(S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride
CAS No.	2007940-85-2
Molecular Formula	C14H21N2O3·HCl
Molecular Weight	308.79 g/mol
Synonyms	(S)-4-(2,4-Dimethoxybenzyl)-3-methyl-2-oxopiperazine hydrochloride; (3S)-4-[(2,4-Dimethoxyphenyl)methyl]-3-methylpiperazin-2-one hydrochloride; (S)-3-Methyl-4-(2,4-dimethoxybenzyl)piperazin-2-one HCl; 2007940-85-2; (S)-enantiomer of 4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.