Description

2-(4-Methylpiperazin-1-yl)ethane-1,1-diol dihydrochloride is a high-purity, functionalized piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) due to its piperazine-based pharmacophore.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex amines and functionalized heterocycles in fine chemical production.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) or other targeted therapeutic agents.
• Ligand Synthesis: Employed in the preparation of ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(4-Methylpiperazin-1-yl)ethane-1,1-diol dihydrochloride
CAS No.	2007916-67-6
Molecular Formula	C7H18Cl2N2O2
Molecular Weight	233.14 g/mol
Synonyms	1,1-Ethanediol, 2-(4-methyl-1-piperazinyl)-, dihydrochloride; 2-(4-Methylpiperazin-1-yl)ethane-1,1-diol hydrochloride; 2-(4-Methyl-1-piperazinyl)-1,1-ethanediol dihydrochloride; 2-(4-Methylpiperazinyl)ethane-1,1-diol dihydrochloride; N-Methylpiperazine ethanol diol dihydrochloride; (2-Hydroxy-2-(4-methylpiperazin-1-yl)ethyl) dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-yl)ethane-1,1-diol dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.