Description

1-(4-Fluorophenyl)-3-[4-(4-Fluorophenyl)Piperazin-1-Yl]Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine-2,5-dione (succinimide) core linked to a fluorinated phenylpiperazine moiety. This compound matters for its critical role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric therapeutic areas. Pharmaceutical R&D teams, fine chemical manufacturers, and contract research organizations (CROs) require this precise building block to synthesize and evaluate new drug candidates with potential receptor-modulating activity.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel psychotropic and neuroactive drug candidates.
• Biochemical Research: Used in pharmacological studies to investigate structure-activity relationships (SAR) for targets such as serotonin and dopamine receptors.
• Medicinal Chemistry: A vital building block for constructing complex molecular libraries for high-throughput screening (HTS) in drug discovery programs.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing processes.
• Custom Synthesis: Provides a specialized starting material for the contract synthesis of proprietary compounds for clinical trials.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[4-(4-Fluorophenyl)Piperazin-1-Yl]Pyrrolidine-2,5-Dione
CAS No.	299949-37-4
Molecular Formula	C20H19F2N3O2
Molecular Weight	371.38 g/mol
Synonyms	1-(4-Fluorophenyl)-3-[4-(4-fluorophenyl)-1-piperazinyl]-2,5-pyrrolidinedione; 3-[4-(4-Fluorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione; 299949-37-4; 1-(4-Fluorophenyl)-3-[4-(4-fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione; 1-(4-Fluorophenyl)-3-[4-(4-fluorophenyl)-1-piperazinyl]-2,5-dihydropyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-[4-(4-Fluorophenyl)Piperazin-1-Yl]Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.