Description

1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-3-Methylpiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific aromatic and heterocyclic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its unique trifluoromethyl and nitro-substituted phenyl ring offers valuable chemical functionality. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology-related APIs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Chemical Synthesis: Serves as a versatile building block for creating more complex piperazine and aniline derivatives in organic chemistry.
• Life Science Research: Employed in biochemical and pharmacological studies as a reference standard or a tool compound for target validation.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials with specific electronic or photophysical properties.

Basic Information

Product Name	1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-3-Methylpiperazine Hydrochloride
CAS No.	299426-31-6
Molecular Formula	C12H14F3N3O2 • HCl
Molecular Weight	325.71 g/mol (Free base: 289.26 g/mol)
Synonyms	3-Methyl-1-[2-nitro-4-(trifluoromethyl)phenyl]piperazine hydrochloride; 1-(2-Nitro-4-trifluoromethylphenyl)-3-methylpiperazine HCl; 299426-31-6; 3-Methyl-1-(2-nitro-4-(trifluoromethyl)phenyl)piperazine monohydrochloride; 1-(2-Nitro-4-(trifluoromethyl)phenyl)-3-methylpiperazine hydrochloride; N-(2-Nitro-4-(trifluoromethyl)phenyl)-N'-methylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-3-Methylpiperazine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.