Description

3-(4-Benzylpiperazin-1-Yl)-1-(2-Methoxyphenyl)Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. It is essential for R&D chemists and process development scientists in pharmaceutical and biotechnology companies seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting neurological receptors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• CNS Drug Discovery: Serves as a core scaffold for developing compounds aimed at treating disorders of the central nervous system.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	3-(4-Benzylpiperazin-1-Yl)-1-(2-Methoxyphenyl)Pyrrolidine-2,5-Dione
CAS No.	299408-83-6
Molecular Formula	C22H25N3O3
Molecular Weight	379.46 g/mol
Synonyms	1-(2-Methoxyphenyl)-3-(4-benzylpiperazin-1-yl)pyrrolidine-2,5-dione; 3-(4-Benzyl-1-piperazinyl)-1-(2-methoxyphenyl)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 3-(4-benzyl-1-piperazinyl)-1-(2-methoxyphenyl)-; UNII-9V8I2B6Q4F; 9V8I2B6Q4F; BRN 12354345; CHEMBL3185142
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Benzylpiperazin-1-Yl)-1-(2-Methoxyphenyl)Pyrrolidine-2,5-Dione is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting regulatory filings for preclinical and clinical development. Certificates of Analysis (COA) with full chromatographic data (HPLC/GC) and spectroscopic confirmation are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.