Description

4-(1H-Benzoimidazol-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a benzimidazole-piperazine scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system disorders.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in biological systems.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-(1H-Benzoimidazol-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	295341-56-9
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	tert-Butyl 4-(1H-benzimidazol-2-yl)piperazine-1-carboxylate; 4-(1H-Benzimidazol-2-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(1H-benzimidazol-2-yl)piperazine; 1-(tert-Butoxycarbonyl)-4-(1H-benzimidazol-2-yl)piperazine; 4-(1H-Benzoimidazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester; 295341-56-9; 4-(1H-Benzo[d]imidazol-2-yl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(1H-Benzoimidazol-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.