Description

4-Thiocarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with a reactive thiocarbamoyl group and a Boc-protected amine, enabling precise molecular construction. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex molecules, particularly in medicinal chemistry for creating libraries of potential drug candidates.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique sulfur-containing functional group.
• Chemical Biology & Proteomics: Acts as a valuable reagent for bioconjugation and the synthesis of chemical probes targeting biological pathways.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of bespoke, high-value compounds for client-specific projects.
• Material Science Research: Investigated as a monomer or precursor for novel polymers and functional materials.

Basic Information

Product Name	4-Thiocarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	294622-55-2
Molecular Formula	C12H21N3O3S
Molecular Weight	287.38 g/mol
Synonyms	1-Boc-4-(thiocarbamoylmethyl)piperazine; tert-Butyl 4-(thiocarbamoylmethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(thiocarbamoylmethyl)piperazine; 4-(Aminothioxomethyl)methyl-1-N-Boc-piperazine; Piperazine-1-carboxylic acid, 4-[(aminothioxomethyl)methyl]-, 1,1-dimethylethyl ester; 294622-55-2; Boc-4-piperazinylmethylthioamide
EINECS	Contact for details

Quality Control

Our production of 4-Thiocarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) are supplied with every shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.