Description

1-(4-Trifluoromethylphenyl)Piperazine Hydrochloride is a high-purity, versatile pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers for the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric drug research.
• Chemical Synthesis: Used as a versatile reagent for introducing the 1-(4-trifluoromethylphenyl)piperazine moiety into larger molecular structures.
• Medicinal Chemistry Research: Serves as a standard or starting material in structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies investigating receptor-ligand interactions and other biochemical pathways.
• Fine Chemical Production: An intermediate in the manufacture of specialty chemicals and advanced materials.

Basic Information

Product Name	1-(4-Trifluoromethylphenyl)Piperazine Hydrochloride
CAS No.	294210-80-3
Molecular Formula	C11H14ClF3N2
Molecular Weight	266.69 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]piperazine hydrochloride; 4-(4-Trifluoromethylphenyl)piperazine hydrochloride; 1-(4-(Trifluoromethyl)phenyl)piperazine HCl; p-Trifluoromethylphenylpiperazine hydrochloride; TFMPP hydrochloride; 4-(Trifluoromethyl)phenylpiperazine hydrochloride; 1-(4-Trifluoromethylphenyl)piperazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethylphenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.