Description

(S)-(2,3,4,5-Tetrahydro-1H-Benzo[B]Azepin-5-Yl)Amine is a chiral benzazepine derivative, a high-value building block in modern organic synthesis. Its significance lies in its role as a key intermediate for the development of novel pharmaceuticals, particularly in the creation of active pharmaceutical ingredients (APIs) with specific stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize complex molecules with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of central nervous system (CNS) active drugs and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral scaffold in the study of novel catalytic processes.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-(2,3,4,5-Tetrahydro-1H-Benzo[B]Azepin-5-Yl)Amine
CAS No.	294196-07-9
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(5S)-2,3,4,5-Tetrahydro-1H-1-benzazepin-5-amine; (S)-5-Amino-2,3,4,5-tetrahydro-1H-1-benzazepine; (S)-5-Amino-1,2,3,4-tetrahydro-1-benzazepine; (S)-Tebazepine amine; (S)-5-Aminotetrahydrobenzazepine; (S)-Benzoazepin-5-amine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this chiral intermediate, with a focus on enantiomeric purity and chemical identity. Each batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and enantiomeric excess is provided with every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.