Description

1-[3-(4-Hydroxy-3-Methoxyphenyl)-Oxo-2-Propenyl]-Piperazine is a specialized piperazine derivative featuring a vanillin-based chalcone structure, making it a valuable synthetic intermediate. This compound matters for its role in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting neurological or inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new analogs with optimized properties.
• Bioconjugate Development: Serves as a linker or spacer molecule in the creation of antibody-drug conjugates (ADCs) or other targeted therapies.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic molecules for high-value applications.
• Agrochemical Research: Potential precursor in the development of new crop protection agents or plant growth regulators.
• Academic & Institutional R&D: Used in university and government laboratories for fundamental research in organic and bioorganic chemistry.

Basic Information

Product Name	1-[3-(4-Hydroxy-3-Methoxyphenyl)-Oxo-2-Propenyl]-Piperazine
CAS No.	292821-46-6
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	1-(3-(4-Hydroxy-3-methoxyphenyl)-3-oxoprop-1-en-1-yl)piperazine; (E)-1-(3-(4-Hydroxy-3-methoxyphenyl)-3-oxoprop-1-en-1-yl)piperazine; 1-(3-Oxo-3-(4-hydroxy-3-methoxyphenyl)prop-1-en-1-yl)piperazine; Vanillin chalcone piperazine derivative; 4-Hydroxy-3-methoxycinnamoylpiperazine; Piperazine, 1-[3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]-; 292821-46-6
EINECS	Contact for details

Quality Control

Our 1-[3-(4-Hydroxy-3-Methoxyphenyl)-Oxo-2-Propenyl]-Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and physical characterization. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.