Description

3-Chloro-2,4,5,6-Tetrafluorobenzoyl Chloride is a highly reactive and versatile fluorinated aromatic building block. This compound is critical for introducing the unique 3-chloro-2,4,5,6-tetrafluorobenzoyl moiety into target molecules, enabling the synthesis of advanced materials and active ingredients with tailored properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the fluorinated benzoyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing chemical resistance, reducing surface energy, and improving material performance.
• Organic Synthesis Reagent: Acts as a versatile acylating agent in Friedel-Crafts and other coupling reactions to create complex fluorinated aromatic ketones and amides.

Basic Information

Product Name	3-Chloro-2,4,5,6-Tetrafluorobenzoyl Chloride
CAS No.	292621-58-0
Molecular Formula	C7Cl2F4O
Molecular Weight	246.98 g/mol
Synonyms	2,4,5,6-Tetrafluoro-3-chlorobenzoyl chloride; 3-Chlorotetrafluorobenzoyl chloride; Benzoyl chloride, 3-chloro-2,4,5,6-tetrafluoro-; 3-Chloro-2,4,5,6-tetrafluorobenzoic acid chloride; Perfluorochlorobenzoyl Chloride (partial); TFCBC (abbrev.)
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2,4,5,6-Tetrafluorobenzoyl Chloride is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.