Description

1,3,4,5-Tetrahydro-3-(4-Piperidinyl)-2H-1,3-Benzodiazepin-2-One is a high-purity pharmaceutical intermediate and research chemical with the CAS number 291509-61-0. This compound is a key building block in the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) drug discovery pipeline. It is essential for medicinal chemistry research and development, serving as a critical precursor for pharmaceutical manufacturers and advanced research institutions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Serves as a key building block for developing potential therapeutics targeting neurological and psychiatric disorders.
• Biochemical Research: Employed as a reference standard or ligand in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological research.

Basic Information

Item	Details
Product Name	1,3,4,5-Tetrahydro-3-(4-Piperidinyl)-2H-1,3-Benzodiazepin-2-One
CAS No.	291509-61-0
Molecular Formula	C15H19N3O
Molecular Weight	257.33 g/mol
Synonyms	3-(4-Piperidinyl)-1,3,4,5-tetrahydro-2H-1,3-benzodiazepin-2-one; 1,3,4,5-Tetrahydro-3-(piperidin-4-yl)-2H-1,3-benzodiazepin-2-one; 291509-61-0; 3-(Piperidin-4-yl)-1,3,4,5-tetrahydro-2H-1,3-benzodiazepin-2-one; 2H-1,3-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-3-(4-piperidinyl)-; 3-(4-Piperidyl)-1,3,4,5-tetrahydro-2H-1,3-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 1,3,4,5-Tetrahydro-3-(4-Piperidinyl)-2H-1,3-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.