Description

(S)-n-(1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Pyrazine-2-Carboxamide is a high-purity chiral intermediate with significant value in advanced pharmaceutical synthesis. This compound is critical for research and development in creating targeted therapeutics due to its specific stereochemistry and functional groups. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting metabolic and neurological pathways.
• Peptidomimetic Research: Used in the design and development of peptide-like molecules with enhanced stability and bioavailability for therapeutic applications.
• Chiral Catalyst Ligand Synthesis: Serves as a precursor for ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Bioconjugation Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Medicinal Chemistry R&D: A valuable scaffold for structure-activity relationship (SAR) studies and high-throughput screening in drug discovery programs.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-n-(1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Pyrazine-2-Carboxamide
CAS No.	289472-80-6
Molecular Formula	C14H14N4O2
Molecular Weight	270.29 g/mol
Synonyms	(S)-2-(Pyrazine-2-carboxamido)-3-phenylpropionamide; (S)-2-(Pyrazine-2-ylcarbonylamino)-3-phenylpropionamide; (S)-N-(1-Amino-3-phenyl-1-oxopropan-2-yl)pyrazine-2-carboxamide; (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (S)-N-(2-Amino-2-oxo-1-phenylethyl)pyrazine-2-carboxamide; L-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; 289472-80-6
EINECS	Contact for details

Quality Control

Our (S)-n-(1-Amino-1-Oxo-3-Phenylpropan-2-Yl)Pyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.