Description

Cyclobutaneacetaldehyde, 3-Formyl-2,2-Dimethyl-, (1R,3R)- (9Ci) is a high-purity, chiral aldehyde building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclobutane core and stereodefined functional groups, which are crucial for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals where stereochemistry is a critical design parameter. CAS No. 288848-36-2.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific herbicides, fungicides, and insecticides where the defined spatial orientation enhances biological activity.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing sophisticated chiral ligands and organocatalysts used in enantioselective transformations.
• Fragrance & Flavor Chemistry: Employed in the development of unique, high-value aroma chemicals that leverage its constrained ring structure for novel olfactory profiles.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with specific thermal and mechanical properties derived from the cyclobutane ring.
• Academic & Process Chemistry: A valuable tool for methodological studies in organic synthesis, including cycloaddition reactions and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	Cyclobutaneacetaldehyde, 3-Formyl-2,2-Dimethyl-, (1R,3R)- (9Ci)
CAS No.	288848-36-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R,3R)-3-Formyl-2,2-dimethylcyclobutaneacetaldehyde; (1R,3R)-2,2-Dimethyl-3-formylcyclobutaneacetaldehyde; (1R,3R)-rel-3-Formyl-2,2-dimethylcyclobutaneacetic aldehyde; (1R,3R)-3-Formyl-2,2-dimethylcyclobutan-1-ylacetaldehyde; Cyclobutaneacetaldehyde, 3-formyl-2,2-dimethyl-, (1R,3R)-; (1R,3R)- enantiomer of 288848-36-2
EINECS	Contact for details

Quality Control

Our Cyclobutaneacetaldehyde, 3-Formyl-2,2-Dimethyl-, (1R,3R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,3R)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.