Description

Surinabant CAS NO 288104-79-0 is a selective cannabinoid receptor 1 (CB1) antagonist, representing a significant compound for research into metabolic and neurological pathways. Its primary value lies in its targeted mechanism of action, which makes it a crucial tool for pharmaceutical and academic research. This product is essential for researchers and developers in the fields of pharmacology, neuroscience, and metabolic disorder research, where precise receptor interaction studies are required.

Application

• Pharmacological Research: A key reference standard and active pharmaceutical ingredient (API) intermediate for studying CB1 receptor antagonism.
• Drug Discovery Programs: Used in high-throughput screening and lead optimization for developing therapeutics targeting obesity, metabolic syndrome, and substance abuse disorders.
• Neuroscience Studies: Employed in preclinical research to investigate the endocannabinoid system's role in appetite regulation, pain perception, and mood.
• Biochemical Assay Development: Serves as a critical control compound in developing and validating in vitro and in vivo assay systems.
• Academic Research: Utilized in university and institutional labs for fundamental studies on receptor-ligand interactions and signal transduction pathways.

Basic Information

Product Name	Surinabant
CAS No.	288104-79-0
Molecular Formula	C₂₅H₂₅Cl₂N₃O₂
Molecular Weight	470.39 g/mol
Synonyms	SR147778; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; Surinabant (SR147778); SR 147778; 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-
EINECS	Contact for details

Quality Control

Our Surinabant is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.