Description

tert-Butyl (1-(Methylsulfonyl)Piperidin-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core functionalized with a carbamate protecting group and a methylsulfonyl moiety. This compound is of significant value for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular scaffolds in drug discovery programs.
• Protease & Kinase Inhibitor Synthesis: Employed in the synthesis of targeted inhibitors for various disease pathways.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of candidate drugs under GMP or non-GMP conditions.
• Chemical Biology: Utilized in the development of chemical probes for studying biological processes and target validation.
• Academic Research: Serves as a starting material for novel organic transformations and methodology development in university laboratories.

Basic Information

Product Name	tert-Butyl (1-(Methylsulfonyl)Piperidin-4-Yl)Carbamate
CAS No.	287953-38-2
Molecular Formula	C12H24N2O4S
Molecular Weight	292.40 g/mol
Synonyms	1-BOC-4-Amino-1-(methylsulfonyl)piperidine; tert-Butyl N-[1-(methylsulfonyl)piperidin-4-yl]carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(methylsulfonyl)piperidine; 1-(Methylsulfonyl)piperidin-4-amine, N-BOC derivative; BOC-4-Amino-1-methylsulfonylpiperidine; 4-(Boc-amino)-1-(methylsulfonyl)piperidine; 1-Boc-4-amino-1-methanesulfonylpiperidine; N-Boc-1-(methylsulfonyl)piperidin-4-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-(Methylsulfonyl)Piperidin-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.