Description

(R)-Piperazine-2-Carboxylic Acid 2L-Csa is a high-purity, non-natural chiral amino acid derivative, serving as a critical building block in asymmetric synthesis. Its primary value lies in its role as a key intermediate for the development of novel pharmaceuticals, particularly in the creation of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality chiral synthons for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of protease inhibitors, kinase inhibitors, and other targeted therapeutics.
• Asymmetric Synthesis: Used as a ligand or catalyst precursor in enantioselective catalytic reactions to produce optically pure compounds.
• Peptidomimetics Development: Incorporated into peptide backbones to create stable, bioactive analogs with enhanced metabolic stability.
• Chemical Biology Research: Serves as a probe or scaffold in the study of enzyme mechanisms and protein-ligand interactions.
• Agrochemical Synthesis: Intermediate in the production of chiral, biologically active crop protection agents.
• Material Science: Potential monomer for creating specialized polymers with unique chiral properties.

Basic Information

Product Name	(R)-Piperazine-2-Carboxylic Acid 2L-Csa
CAS No.	278790-39-9
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(R)-2-Piperazinecarboxylic Acid; D-Pipecolic Acid; (R)-Piperazine-2-carboxylic Acid; (2R)-Piperazine-2-carboxylic Acid; (R)-Hexahydropyrazine-2-carboxylic Acid; 2L-Csa; (R)-PCA; (R)-Aminopiperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our (R)-Piperazine-2-Carboxylic Acid 2L-Csa is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.