Description

Cyclohexanemethanol, 2-Ethynyl-, (1R,2R)-Rel- (9Ci) is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and specialty materials. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for the development of novel therapeutics, particularly in areas requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development and screening of new asymmetric catalytic reactions.
• Advanced Material Synthesis: Employed in the creation of specialty polymers and liquid crystals where the rigid, functionalized cyclohexane core imparts specific structural and optical properties.
• Agrochemical Development: Acts as a building block for novel, enantiopure pesticides and herbicides, leveraging its defined stereochemistry for targeted biological activity.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, particularly in reactions involving alkynes and chiral alcohols.

Basic Information

Product Name	Cyclohexanemethanol, 2-Ethynyl-, (1R,2R)-Rel- (9Ci)
CAS No.	275386-65-7
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	(1R,2R)-2-Ethynylcyclohexanemethanol; rel-(1R,2R)-2-Ethynylcyclohexylmethanol; (1R,2R)-2-Ethynyl-1-cyclohexanemethanol; 2-Ethynylcyclohexanemethanol (rel-(1R,2R)-form); Cyclohexanemethanol, 2-ethynyl-, (1R,2R)-rel-; Chiral Ethynyl Cyclohexanemethanol; (1R,2R)-2-Ethynyl-cyclohexanemethanol
EINECS	Contact for details

Quality Control

Our Cyclohexanemethanol, 2-Ethynyl-, (1R,2R)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.