Description

Cyclohexanecarboxaldehyde, 2-Ethynyl-, (1R,2R)-Rel- (9Ci) is a chiral, enantiomerically pure aldehyde building block featuring both an aldehyde and an ethynyl functional group on a cyclohexane backbone. This compound is valued for its role in asymmetric synthesis, enabling the construction of complex, stereodefined molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule is critical for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) used in enantioselective catalysis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Academic & Industrial R&D: A versatile building block in exploratory organic synthesis for constructing complex natural product analogs and chemical libraries.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 2-Ethynyl-, (1R,2R)-Rel- (9Ci)
CAS No.	275386-64-6
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	(1R,2R)-2-Ethynylcyclohexanecarboxaldehyde; rel-(1R,2R)-2-Ethynylcyclohexanecarbaldehyde; 2-Ethynylcyclohexanecarboxaldehyde, (1R,2R)-rel-; (1R,2R)-rel-2-Ethynylcyclohexanecarboxaldehyde; 275386-64-6; (1R,2R)-2-Ethynyl-1-cyclohexanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxaldehyde, 2-Ethynyl-, (1R,2R)-Rel- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the material should be kept away from oxidizing agents and used promptly once the original container is opened.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.