Description

Taspoglutide CAS NO 275371-94-3 is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist, representing a significant advancement in peptide-based therapeutic research. This compound is of critical importance for pharmaceutical development due to its potential role in regulating blood glucose levels and promoting insulin secretion. It is primarily required by pharmaceutical R&D departments, biotechnology firms, and contract research organizations (CROs) engaged in developing novel treatments for type 2 diabetes and metabolic disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in the research and development of next-generation injectable anti-diabetic medications.
• Preclinical & Clinical Research: Used as a reference standard and investigational material in metabolic disease studies, including pharmacokinetics and pharmacodynamics.
• Biochemical Research: Serves as a high-purity tool compound for studying GLP-1 receptor signaling pathways and mechanisms of action.
• Formulation Development: Employed in the development of stable, long-acting peptide formulations, including lyophilized powders and sustained-release delivery systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related peptide products.

Basic Information

Product Name	Taspoglutide
CAS No.	275371-94-3
Molecular Formula	C₁₇₂H₂₆₅N₄₅O₅₅
Molecular Weight	4108.2 g/mol (monoisotopic)
Synonyms	R1583; BIM-51077; Taspoglutide acetate; GLP-1 (7-36) amide, Lys^(26)-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-Arg^(34)-; (8-34)Peptide; Glucagon-like peptide 1 agonist; BIM51077; BIM 51077
EINECS	Contact for details

Quality Control

Our Taspoglutide is manufactured under strict quality management systems to ensure the highest standards of purity and consistency for research and development. Each batch is subjected to a comprehensive battery of analytical tests, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment. We support development work aligned with ICH guidelines and cGMP principles for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive). For long-term stability, store desiccated at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. Store in a cool, dry, and well-ventilated area dedicated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	3.0% - 10.0%
Bacterial Endotoxins	< 1.0 EU/mg
Sterility (for sterile grade)	Sterile (upon request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.