Description

Pyrrolo[1,2-A]Pyrazine-1-Carboxylic Acid, Octahydro-, (1S,8As)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its rigid, fused bicyclic structure and functional handle, making it a critical intermediate for constructing complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used as a versatile building block for constructing focused libraries and exploring structure-activity relationships (SAR) due to its constrained conformation.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, or insecticides where its unique heterocyclic core can contribute to biological activity.
• Process Chemistry & Scale-Up: Acts as a starting material or advanced intermediate in the development of efficient, scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or biological pathways.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1-Carboxylic Acid, Octahydro-, (1S,8As)- (9Ci)
CAS No.	273223-57-7
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(1S,8aS)-Octahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid; (1S,8aS)-Octahydro-1H-pyrrolo[1,2-a]pyrazine-1-carboxylic acid; (1S,8aS)-1,2,3,4,6,7,8,8a-Octahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid; (S)-Octahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid; Pyrrolo[1,2-a]pyrazine-1-carboxylic acid, octahydro-, (1S,8aS)-; 273223-57-7; (1S,8aS)-perhydropyrrolo[1,2-a]pyrazine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-1-Carboxylic Acid, Octahydro-, (1S,8As)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile data is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.