Description

1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphoglycerol, Ammonium Salt is a high-purity, synthetic phospholipid, specifically a phosphatidylglycerol (PG) derivative. This compound is a critical component for constructing biomimetic membranes and liposomal drug delivery systems due to its anionic charge and structural similarity to natural cell membrane lipids. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid composition for formulation stability and efficacy.

Application

• Liposomal Drug Delivery: A key excipient for creating stable, anionic liposomes to encapsulate and deliver therapeutic agents, including mRNA, siRNA, and small molecule drugs.
• Biomimetic Membrane Research: Used to create model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and fusion processes.
• Pharmaceutical Formulations: Serves as a functional lipid component in injectable and topical formulations to enhance drug solubility and target specificity.
• Diagnostic Assays: Incorporated into lipid-based reagents and sensors for diagnostic applications requiring specific membrane surface properties.
• Biophysical Studies: Utilized in calorimetry, spectroscopy, and microscopy to investigate lipid bilayer thermodynamics, phase behavior, and structure.
• Cosmetic Actives Carrier: Employed in advanced cosmetic formulations for the encapsulation and controlled release of active ingredients.

Basic Information

Item	Detail
Product Name	1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphoglycerol, Ammonium Salt
CAS No.	267228-70-6
Molecular Formula	C41H80NO10P
Molecular Weight	778.05 g/mol
Synonyms	POPG (Ammonium Salt); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (ammonium salt); (16:0-18:1) PG; POPG-NH4; PG(16:0/18:1); Phosphatidylglycerol (16:0/18:1) ammonium salt; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) ammonium salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphoglycerol, Ammonium Salt is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high purity, identity, and consistency, meeting the stringent requirements for research and pharmaceutical development. Comprehensive Certificates of Analysis (COA) detailing purity, lipid profile, and critical impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Total Lipid)
Purity (TLC)	Single spot
Fatty Acid Composition	Conforms to 16:0 / 18:1 (cis-9)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines
Ammonium Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.