Description

R-(-)-2-(4-Isobutylphenyl)Propionyl Methansulphonamide, Lysine Salt is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate, specifically the lysine salt form of a key chiral precursor. This compound is critical for ensuring the enantiomeric purity and bioavailability of advanced pharmaceutical actives. It is primarily required by pharmaceutical R&D laboratories and manufacturing facilities engaged in the synthesis of novel, optically pure therapeutic agents.

Application

• Key Chiral Intermediate in the synthesis of enantiomerically pure NSAIDs and related anti-inflammatory agents.
• Pharmaceutical Research & Development for exploring new drug candidates with improved efficacy and reduced side-effect profiles.
• Process Chemistry & Scale-up for the commercial production of targeted active pharmaceutical ingredients (APIs).
• Reference Standard for analytical method development and quality control in chiral separation techniques.
• Precursor for Prodrug Development, leveraging the lysine salt to enhance solubility and pharmacokinetic properties.

Basic Information

Product Name	R-(-)-2-(4-Isobutylphenyl)Propionyl Methansulphonamide, Lysine Salt
CAS No.	266359-93-7
Molecular Formula	C20H34N2O5S
Molecular Weight	414.56 g/mol
Synonyms	(R)-2-(4-Isobutylphenyl)propionyl methanesulfonamide lysine salt; (R)-Flurbiprofenyl Methanesulfonamide Lysine Salt; Lysine salt of R-(-)-2-(4-Isobutylphenyl)propionyl methanesulfonamide; (2R)-2-[4-(2-Methylpropyl)phenyl]propanoic acid, 2-(methylsulfonyl)amino]-2-oxoethyl ester, lysine salt; R-(-)-Flurbiprofen Methanesulfonamide Lysinate; L-Lysine, compd. with N-[[(1R)-1-[4-(2-methylpropyl)phenyl]ethyl]carbonyl]methanesulfonamide (1:1)
EINECS	Contact for details

Quality Control

Our R-(-)-2-(4-Isobutylphenyl)Propionyl Methansulphonamide, Lysine Salt is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.