Description

Methyl 5,6,7,8-Tetrahydropyrido[4,3-B]Pyrazine-7-Carboxylate Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring complex heterocyclic scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need it to enable efficient, scalable synthesis routes for potential drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and process development of new APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Methyl 5,6,7,8-Tetrahydropyrido[4,3-B]Pyrazine-7-Carboxylate Hydrochloride
CAS No.	264624-28-4
Molecular Formula	C10H14N3O2·HCl
Molecular Weight	245.70 g/mol (Free base: 209.24 g/mol)
Synonyms	Methyl 5,6,7,8-tetrahydropyrido[4,3-b]pyrazine-7-carboxylate HCl; 7-Pyridinecarboxylic acid, 5,6,7,8-tetrahydro-3-methyl-, methyl ester, hydrochloride; Methyl 7-carboxy-5,6,7,8-tetrahydropyrido[4,3-b]pyrazine hydrochloride; 264624-28-4; Pyrido[4,3-b]pyrazine-7-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester, hydrochloride; Tetrahydro-pyrido[4,3-b]pyrazine-7-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 5,6,7,8-Tetrahydropyrido[4,3-B]Pyrazine-7-Carboxylate Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and confirm compliance with stringent in-house specifications suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.