Description

2-(Trifluoromethyl)-4-(Piperazin-1-Yl)Benzonitrile is a high-value, multi-functional chemical intermediate featuring a benzonitrile core substituted with a trifluoromethyl group and a piperazine ring. This compound matters for its unique structural motifs, which are critical for imparting desirable properties like metabolic stability and enhanced binding affinity in advanced molecular design. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in drug discovery programs targeting central nervous system (CNS) disorders and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially for neurological and psychiatric conditions.
• Agrochemical Research: Used in developing new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty polymers and advanced organic materials requiring specific electronic or structural properties.
• Chemical Synthesis: Employed in organic chemistry research to introduce the piperazine and trifluoromethyl motifs into more complex molecular architectures.
• Ligand & Catalyst Development: Useful in creating novel ligands for catalysis or in medicinal chemistry for probing biological targets.

Basic Information

Product Name	2-(Trifluoromethyl)-4-(Piperazin-1-Yl)Benzonitrile
CAS No.	262295-57-8
Molecular Formula	C12H12F3N3
Molecular Weight	255.24 g/mol
Synonyms	4-(Piperazin-1-yl)-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-4-piperazin-1-ylbenzonitrile; 4-Piperazinyl-2-(trifluoromethyl)benzonitrile; 2-Trifluoromethyl-4-piperazinobenzonitrile; 262295-57-8; 4-(1-Piperazinyl)-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-4-(1-piperazinyl)benzonitrile; Benzonitrile, 4-(1-piperazinyl)-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-4-(Piperazin-1-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.