Description

2H-Pyrido[1,2-A]Pyrazine-1,4(3H,6H)-Dione,Tetrahydro-8-Hydroxy-,(8S,9Ar)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a critical chiral building block and synthetic intermediate for the development of novel pharmacologically active agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective reactions to introduce the (8S,9aR) configuration into target molecules.
• Academic Research: Serves as a model compound in studies focusing on heterocyclic chemistry, reaction mechanisms, and the synthesis of novel fused ring systems.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-1,4(3H,6H)-Dione,Tetrahydro-8-Hydroxy-,(8S,9Ar)-(9Ci)
CAS No.	262289-72-5
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	(8S,9aR)-8-Hydroxy-1,2,3,4,6,7,8,9a-octahydropyrido[1,2-a]pyrazine-1,4-dione; Tetrahydro-8-hydroxy-2H-pyrido[1,2-a]pyrazine-1,4(3H,6H)-dione, (8S,9aR)-; (8S,9aR)-Tetrahydro-8-hydroxy-2H-pyrido[1,2-a]pyrazine-1,4(3H,6H)-dione; 262289-72-5; (8S,9aR)-Octahydropyrido[1,2-a]pyrazine-1,4-dione derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.