Description

2-(4-Aminophenyl)-1,2-Dihydro-7-[(1-Oxido-2-Pyridinyl)Methoxy]-1-Oxo-4-(3,4,5-Trimethoxyphenyl)-3-Isoquinolinecarboxylic Acid Methyl Ester Monohydrochloride is a high-purity, complex heterocyclic compound designed for advanced research and development. This specialized chemical is critical for pharmaceutical and agrochemical innovators seeking to develop novel active ingredients with targeted biological activity. It serves as a key advanced intermediate or reference standard for scientists in medicinal chemistry, process development, and analytical laboratories.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a reference compound or precursor for structure-activity relationship (SAR) studies and lead optimization.
• Process Development & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Provides a high-purity benchmark for method development, validation, and quality control (HPLC, LC-MS) in regulatory submissions.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with specific modes of action.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study specific biological pathways and enzyme interactions.

Basic Information

Item	Detail
Product Name	2-(4-Aminophenyl)-1,2-Dihydro-7-[(1-Oxido-2-Pyridinyl)Methoxy]-1-Oxo-4-(3,4,5-Trimethoxyphenyl)-3-Isoquinolinecarboxylic Acid Methyl Ester Monohydrochloride
CAS No.	260414-73-1
Molecular Formula	C32H30ClN3O8
Molecular Weight	620.05 g/mol
Synonyms	7-[(1-Oxido-2-pyridinyl)methoxy]-2-(4-aminophenyl)-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic acid methyl ester hydrochloride; Methyl 2-(4-aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate hydrochloride; CAS 260414-73-1; 2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic acid methyl ester HCl; 3-Isoquinolinecarboxylic acid, 2-(4-aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-, methyl ester, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.