Description

Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-4-Oxo-, (1S,2R,5R,6R)- is a high-purity, stereochemically defined bicyclic amino acid derivative with significant synthetic utility. This compound serves as a sophisticated chiral building block and key intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of complex, constrained peptidomimetics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetic Scaffold: Used to construct conformationally restricted peptide analogs, enhancing metabolic stability and receptor selectivity.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce complex molecular architecture.
• Medicinal Chemistry Research: Serves as a core structure for library synthesis in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and protein-protein interactions.
• Process Chemistry: Investigated for scalable routes in the production of active pharmaceutical ingredients (APIs) requiring this specific stereochemistry.

Basic Information

Item	Details
Product Name	Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-4-Oxo-, (1S,2R,5R,6R)-
CAS No.	260355-41-7
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	(1S,2R,5R,6R)-2-Amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; (1S,2R,5R,6R)-2-Amino-4-oxo-2,6-bicyclo[3.1.0]hexanedicarboxylic Acid; 2-Amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, (1S,2R,5R,6R)-; Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-4-oxo-, (1S,2R,5R,6R)-; 260355-41-7; (1S,2R,5R,6R)-rel-2-Amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-4-Oxo-, (1S,2R,5R,6R)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.