Description

(2S,5R)-1-Benzyl-2,5-Dimethylpiperazine is a chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a crucial chiral building block and ligand for the development of pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring specific stereochemistry.
• Catalyst Ligand: Used as a precursor or component in chiral ligands for asymmetric catalysis, enabling enantioselective transformations in fine chemical manufacturing.
• Agrochemical Research: Employed in the development of novel, stereochemically-defined pesticides and herbicides.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in chiral analysis.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry programs and process chemistry research exploring new synthetic methodologies.

Basic Information

Product Name	(2S,5R)-1-Benzyl-2,5-Dimethylpiperazine
CAS No.	260254-80-6
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	1-Benzyl-2,5-dimethylpiperazine, (2S,5R)-isomer; (2S,5R)-1-Benzyl-2,5-dimethylpiperazine; (2S,5R)-1-(Phenylmethyl)-2,5-dimethylpiperazine; (2S,5R)-Benzyl-2,5-dimethylpiperazine; (2S,5R)-1-Bn-2,5-DMP; (S,R)-1-Benzyl-2,5-dimethylpiperazine; UNII-9Q2T8I2K8F
EINECS	Contact for details

Quality Control

Our (2S,5R)-1-Benzyl-2,5-Dimethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.