Description

(2R,5S)-1-Benzyl-5-Isopropyl-2-Methyl-Piperazine CAS NO 260254-74-8 is a high-purity, stereochemically defined piperazine derivative, a crucial building block in advanced organic synthesis. Its precise chiral configuration makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereoselectivity. This compound is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules, including potential drug candidates and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug molecules, especially for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated ligands for transition metal catalysts in enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel, high-value crop protection agents and pesticides.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(2R,5S)-1-Benzyl-5-Isopropyl-2-Methyl-Piperazine
CAS No.	260254-74-8
Molecular Formula	C15H24N2
Molecular Weight	232.36 g/mol
Synonyms	1-Benzyl-5-isopropyl-2-methylpiperazine, (2R,5S)-isomer; (2R,5S)-1-Benzyl-2-methyl-5-(propan-2-yl)piperazine; (2R,5S)-1-Benzyl-5-(1-methylethyl)-2-methylpiperazine; (2R,5S)-1-Benzyl-5-isopropyl-2-methylpiperazine; (2R,5S)-1-Benzyl-5-isopropyl-2-methyl-piperazine; (2R,5S)-1-Benzyl-5-isopropyl-2-methylpiperazine; 1-Benzyl-5-isopropyl-2-methyl-(2R,5S)-piperazine
EINECS	Contact for details

Quality Control

Our (2R,5S)-1-Benzyl-5-Isopropyl-2-Methyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing full specifications, including enantiomeric excess (ee), is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.