Description

Butyraldehyde 2,4-Dinitrophenylhydrazone-D3 is a deuterium-labeled derivative of the classic 2,4-dinitrophenylhydrazone (2,4-DNPH) derivative of butyraldehyde. This compound is specifically designed for use as a high-purity internal standard in quantitative analytical chemistry, enabling precise and accurate measurements. It is essential for researchers and quality control laboratories in the pharmaceutical, environmental, and food safety sectors who require reliable isotopic dilution techniques for trace analysis of carbonyl compounds. The deuterium label provides a distinct mass spectrometric signature, eliminating interference from the native analyte.

Application

• Internal Standard for Mass Spectrometry (MS): Primary application for the quantitative analysis of butyraldehyde and related aldehydes via GC-MS or LC-MS/MS, ensuring method accuracy and precision.
• Pharmaceutical Impurity Profiling: Used in stability testing and method validation to quantify genotoxic impurity levels of butyraldehyde in active pharmaceutical ingredients (APIs) and finished drug products.
• Environmental Monitoring: Critical for the accurate measurement of volatile organic compounds (VOCs), specifically aldehydes, in air, water, and soil samples as per EPA and other regulatory methods.
• Food and Flavor Analysis: Enables precise quantification of butyraldehyde, a key flavor and spoilage marker, in food products, beverages, and packaging materials.
• Metabolomics and Biochemical Research: Serves as a stable-isotope labeled tracer in metabolic pathway studies involving carbonyl metabolites.
• Method Development and Validation: Provides a reliable reference standard for developing, calibrating, and validating analytical methods for carbonyl compound detection.
• Quality Control in Chemical Synthesis: Used to monitor and control levels of residual butyraldehyde in fine chemicals and industrial intermediates.

Basic Information

Product Name	Butyraldehyde 2,4-Dinitrophenylhydrazone-D3
CAS No.	259824-54-9
Molecular Formula	C₁₀H₁₀D₃N₄O₄
Molecular Weight	240.24 g/mol (approx.)
Synonyms	Butanal 2,4-Dinitrophenylhydrazone-d3; Butyraldehyde-DNPH-d3; n-Butyraldehyde 2,4-DNPH-d3; 2,4-DNPH Derivative of Butyraldehyde-d0 (unlabeled reference); (E)-1-(2,4-Dinitrophenyl)-2-(butylidene-d3)hydrazine; Butanal-2,4-dinitrophenylhydrazone (deuterated); Deuterated Butyraldehyde DNPH; Isotopically Labeled Butyraldehyde Derivative
EINECS	Contact for details

Quality Control

Every batch of Butyraldehyde 2,4-Dinitrophenylhydrazone-D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, confirmed by advanced spectroscopic and chromatographic techniques including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific data for identity, purity (HPLC assay), isotopic enrichment (D-content), and related substances. Our quality commitment ensures consistency and reliability for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.