Description

Propionaldehyde 2,4-Dinitrophenylhydrazone-D3 is a deuterated derivative of the classic 2,4-dinitrophenylhydrazone (2,4-DNPH) derivative of propionaldehyde, serving as a critical analytical standard and reference material. This compound is essential for ensuring accuracy and traceability in quantitative mass spectrometry and chromatographic analyses, particularly where isotope dilution techniques are required. It is primarily utilized by analytical laboratories, environmental testing facilities, and pharmaceutical R&D departments involved in the precise detection and quantification of aldehydes.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterium-labeled internal standard in GC-MS or LC-MS/MS for the accurate quantification of propionaldehyde and related carbonyl compounds via isotope dilution, minimizing matrix effects and improving data reliability.
• Calibration Standard in Chromatography: Serves as a high-purity calibration standard for HPLC and GC methods analyzing carbonyl-DNPH derivatives, essential for method validation and ensuring regulatory compliance in analytical protocols.
• Environmental Air & Water Analysis: Critical for tracing and quantifying volatile organic compounds (VOCs) like propionaldehyde in environmental samples, supporting air quality monitoring and industrial emission testing.
• Food & Beverage Safety Testing: Employed in the analysis of flavor compounds, spoilage markers, or process contaminants where precise measurement of aldehydes is necessary for quality control and safety assessments.
• Pharmaceutical Impurity Profiling: Used in stability studies and impurity characterization of drug substances and products to identify and quantify aldehyde-related degradation products.
• Research & Method Development: A key tool for academic and industrial researchers developing new analytical methods for carbonyl compound detection, derivatization efficiency studies, and metabolic profiling.

Basic Information

Product Name	Propionaldehyde 2,4-Dinitrophenylhydrazone-D3
CAS No.	259824-53-8
Molecular Formula	C9H6D3N4O4
Molecular Weight	226.20 g/mol (approx.)
Synonyms	Propanal 2,4-DNPH-d3; Propionaldehyde-d3 2,4-Dinitrophenylhydrazone; 2,4-DNPH Derivative of Propionaldehyde-d3; (E)-1-(2,4-Dinitrophenyl)-2-propylidene-d3 hydrazine; Deuterated Propionaldehyde DNPH; Propionaldehyde-2,4-dinitrophenylhydrazone (deuterated); C3-Aldehyde-DNPH-d3; Internal Standard for Propionaldehyde Analysis
EINECS	Contact for details

Quality Control

Our Propionaldehyde 2,4-Dinitrophenylhydrazone-D3 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, meeting the exacting requirements of analytical reference standards. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and chromatographic performance. We adhere to relevant industry guidelines for reference materials to ensure reliable and reproducible results in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, cool, and well-ventilated area. Handle and store in accordance with good laboratory practices to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (by area)
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.