Description

Di-tert-Butyl 2-(2-Hydroxyethyl)Piperazine-1,4-Dicarboxylate is a high-purity, functionalized piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecules with tailored properties for demanding applications. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and as a component in linker chemistry for antibody-drug conjugates (ADCs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its piperazine core contributes to biological activity and environmental stability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers, coatings, and resins with enhanced thermal or mechanical properties.
• Ligand and Catalyst Development: The nitrogen and oxygen donor atoms make it a useful scaffold for designing chelating ligands in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its bifunctional (hydroxy and carboxylate) nature.

Basic Information

Product Name	Di-tert-Butyl 2-(2-Hydroxyethyl)Piperazine-1,4-Dicarboxylate
CAS No.	259808-71-4
Molecular Formula	C16H30N2O5
Molecular Weight	330.42 g/mol
Synonyms	1,4-Piperazinedicarboxylic acid, 2-(2-hydroxyethyl)-, 1,4-bis(1,1-dimethylethyl) ester; 2-(2-Hydroxyethyl)piperazine-1,4-dicarboxylic acid di-tert-butyl ester; Di-tert-butyl 2-(2-hydroxyethyl)piperazine-1,4-dicarboxylate; tert-Butyl 2-(2-hydroxyethyl)piperazine-1,4-dicarboxylate; N-Boc-2-(2-hydroxyethyl)piperazine; Boc-protected hydroxyethylpiperazine; 259808-71-4; Hydroxyethyl piperazine Boc derivative
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 2-(2-Hydroxyethyl)Piperazine-1,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.