Description

1-Boc-3,3-Dimethylpiperazine is a high-purity, protected piperazine derivative widely used as a critical building block in advanced organic synthesis. Its value lies in providing a sterically hindered, secondary amine nitrogen that is protected by the acid-labile tert-butoxycarbonyl (Boc) group, enabling selective deprotection in multi-step sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Ligand and Catalyst Preparation: Used to construct sophisticated ligands for asymmetric catalysis and metal complexes due to its sterically demanding and chelating capabilities.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Polymer Chemistry: Incorporated into specialty polymers and dendrimers to modify thermal and mechanical properties.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, linkers, and reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services and scale-up production under cGMP conditions.

Basic Information

Product Name	1-Boc-3,3-Dimethylpiperazine
CAS No.	259808-67-8
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3,3-dimethylpiperazine; tert-Butyl 3,3-dimethylpiperazine-1-carboxylate; 3,3-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; N-Boc-3,3-dimethylpiperazine; Boc-3,3-dimethylpiperazine; 1-Boc-3,3-dimethylpiperazine; 259808-67-8; 1-N-Boc-3,3-dimethylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-3,3-Dimethylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.