Description

1-((4-Chlorophenyl)Sulfonyl)-4-(2-Methoxyphenyl)Piperazine is a high-purity, synthetic organic compound belonging to the sulfonylated piperazine class, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring distinct chlorophenyl and methoxyphenyl moieties, makes it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies in drug discovery projects.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) requiring a sulfonyl piperazine pharmacophore.
• Biochemical Tool Compound: Serves as a reference standard or investigational compound in pharmacological assays and receptor binding studies.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	1-((4-Chlorophenyl)Sulfonyl)-4-(2-Methoxyphenyl)Piperazine
CAS No.	259683-39-1
Molecular Formula	C17H19ClN2O3S
Molecular Weight	366.86 g/mol
Synonyms	1-(4-Chlorobenzenesulfonyl)-4-(2-methoxyphenyl)piperazine; 4-(2-Methoxyphenyl)-1-[(4-chlorophenyl)sulfonyl]piperazine; 1-(p-Chlorophenylsulfonyl)-4-(o-methoxyphenyl)piperazine; N-(4-Chlorophenylsulfonyl)-N'-(2-methoxyphenyl)piperazine; 259683-39-1; 4-(2-Methoxyphenyl)-1-(4-chlorophenylsulfonyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-((4-Chlorophenyl)Sulfonyl)-4-(2-Methoxyphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.