Description

1-Piperazinecarboxamide, n-(3-Chlorophenyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its piperazine and trifluoromethylpyridine motifs.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Potential use as a reference standard or probe in biochemical assays and pharmacological studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for client-specific synthetic routes.

Basic Information

Product Name	1-Piperazinecarboxamide, n-(3-Chlorophenyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	259196-24-2
Molecular Formula	C17H14ClF3N4O
Molecular Weight	382.77 g/mol
Synonyms	N-(3-Chlorophenyl)-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamide; 4-[4-(Trifluoromethyl)-2-pyridinyl]-N-(3-chlorophenyl)-1-piperazinecarboxamide; UNII-9F3Q3F8K2F; 9F3Q3F8K2F; 1-Piperazinecarboxamide, N-(3-chlorophenyl)-4-[4-(trifluoromethyl)-2-pyridinyl]-; BDBM50111657; AKOS005715923; ZINC000003869756
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxamide, n-(3-Chlorophenyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards where required, and specifications can be aligned with client-specific pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.