Description

2-Cyanomethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, protected morpholine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a cyano and a tert-butyl ester group, makes it an invaluable intermediate for constructing complex pharmacophores and fine chemicals. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the morpholine ring contributes to biological activity.
• Peptidomimetic Chemistry: Serves as a constrained scaffold or a protected amino acid analog in the design of peptide-like molecules.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis or as a precursor for functionalized materials.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemists to introduce functional complexity in target molecules.

Basic Information

Product Name	2-Cyanomethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	259180-69-3
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	4-(tert-Butoxycarbonyl)-2-(cyanomethyl)morpholine; tert-Butyl 2-(cyanomethyl)morpholine-4-carboxylate; 2-Cyanomethylmorpholine-4-carboxylic Acid tert-Butyl Ester; Morpholine-4-carboxylic acid, 2-(cyanomethyl)-, 1,1-dimethylethyl ester; BOC-Morpholine-2-acetonitrile; N-Boc-2-cyanomethylmorpholine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyanomethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.