Description

1-Piperazinecarboxamide, n-(1,1-Dimethylethyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-value, specialized heterocyclic compound featuring a piperazine core substituted with a tert-butyl carboxamide and a trifluoromethylpyridinyl group. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents due to the presence of the trifluoromethyl group.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	1-Piperazinecarboxamide, n-(1,1-Dimethylethyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	257862-83-2
Molecular Formula	C15H19F3N4O
Molecular Weight	328.34 g/mol
Synonyms	N-tert-Butyl-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamide; 4-[4-(Trifluoromethyl)-2-pyridinyl]-N-(1,1-dimethylethyl)-1-piperazinecarboxamide; N-(tert-Butyl)-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamide; 257862-83-2; tert-Butyl 4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxylate derivative; 1-Piperazinecarboxamide, N-(1,1-dimethylethyl)-4-[4-(trifluoromethyl)-2-pyridinyl]-; 4-(4-(Trifluoromethyl)pyridin-2-yl)-N-(tert-butyl)piperazine-1-carboxamide
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications, with documentation tailored to meet rigorous audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.