Description

Piperazine, 1-[(4-Chlorophenyl)Sulfonyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a specialized, high-purity sulfonamide derivative of piperazine, designed for advanced synthetic applications. This compound is valued for its unique molecular architecture, which incorporates both a chlorophenylsulfonyl group and a trifluoromethylpyridinyl moiety, making it a critical building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic and diagnostic purposes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a sophisticated scaffold for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Used in the design and synthesis of chemical probes for studying enzyme inhibition and protein-protein interactions.
• Material Science: Investigated as a monomer or additive for creating advanced polymers with specific thermal or chemical resistance properties.
• Contract Research & Development (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	Piperazine, 1-[(4-Chlorophenyl)Sulfonyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	257862-71-8
Molecular Formula	C16H13ClF3N3O2S
Molecular Weight	403.81 g/mol
Synonyms	1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 4-[4-(Trifluoromethyl)-2-pyridinyl]-1-[(4-chlorophenyl)sulfonyl]piperazine; 1-(4-Chlorobenzenesulfonyl)-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 257862-71-8; Piperazine sulfonamide derivative
EINECS	Contact for details

Quality Control

Our production of Piperazine, 1-[(4-Chlorophenyl)Sulfonyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.