Description

Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-value, functionalized piperazine derivative designed for advanced chemical synthesis. This compound matters as a sophisticated building block, offering a unique trifluoromethylpyridinyl moiety and a pivaloyl-like protecting group, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.
• Library Synthesis for High-Throughput Screening: Used to generate diverse compound libraries for the identification of new hits in drug discovery campaigns.

Basic Information

Product Name	Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	257862-69-4
Molecular Formula	C17H22F3N3O
Molecular Weight	341.37 g/mol
Synonyms	1-Pivaloyl-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 4-[4-(Trifluoromethyl)-2-pyridinyl]-1-(3,3-dimethyl-1-oxobutyl)piperazine; 1-(3,3-Dimethylbutyryl)-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 1-(2,2-Dimethylpropionyl)-4-[4-(trifluoromethyl)-2-pyridyl]piperazine; 1-(Pivaloyl)-4-(4-trifluoromethyl-2-pyridinyl)piperazine; PZ-1; PZ-2; TRZ-Piperazine Derivative
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.