Description

Piperazine, 1-[4-(Trifluoromethyl)Benzoyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-value, specialized piperazine derivative featuring dual trifluoromethyl groups, which confer unique physicochemical properties. This compound is critical for its role as a sophisticated pharmaceutical intermediate in the development of novel active ingredients. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, leveraging the bioactivity-enhancing trifluoromethyl groups.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the development of specialty polymers or organic electronic materials due to its aromatic and heterocyclic structure.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP conditions.

Basic Information

Item	Detail
Product Name	Piperazine, 1-[4-(Trifluoromethyl)Benzoyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	257862-66-1
Molecular Formula	C18H13F6N3O
Molecular Weight	401.31 g/mol
Synonyms	1-[4-(Trifluoromethyl)benzoyl]-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 4-[4-(Trifluoromethyl)-2-pyridinyl]-1-[[4-(trifluoromethyl)phenyl]carbonyl]piperazine; 1-(4-(Trifluoromethyl)benzoyl)-4-(4-(trifluoromethyl)pyridin-2-yl)piperazine; 2-[4-[4-(Trifluoromethyl)benzoyl]piperazin-1-yl]-4-(trifluoromethyl)pyridine; CAS 257862-66-1
EINECS	Contact for details

Quality Control

Every batch of our Piperazine, 1-[4-(Trifluoromethyl)Benzoyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.