Description

Cyclohexanecarboxaldehyde, 4-Fluoro-1-Methyl-, cis- (9Ci) is a specialized fluorinated aldehyde building block with a defined stereochemistry. This compound matters as a high-value intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of a fluorine atom and a specific spatial arrangement can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists working on new active ingredients, including potential drugs, crop protection agents, and advanced materials. The CAS number for this compound is 255852-21-2.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel fluorinated drug candidates, potentially targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in constructing advanced, fluorinated active ingredients for crop protection, where fluorine can enhance herbicidal or insecticidal activity, improve rainfastness, and alter degradation profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Advanced Material Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials where the fluorinated cyclohexane moiety can influence thermal stability, dielectric properties, and molecular ordering.
• Flavor and Fragrance Chemistry: Potential use as an intermediate for creating novel, complex aroma chemicals with unique olfactory properties derived from its aldehyde functionality and fluorinated structure.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes to study biological processes and enzyme interactions, leveraging the fluorine atom as a potential NMR-active label.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 4-Fluoro-1-Methyl-, cis- (9Ci)
CAS No.	255852-21-2
Molecular Formula	C8H13FO
Molecular Weight	144.18 g/mol
Synonyms	cis-4-Fluoro-1-methylcyclohexanecarboxaldehyde; (1r,4r)-4-Fluoro-1-methylcyclohexane-1-carbaldehyde; 4-Fluoro-1-methylcyclohexanecarboxaldehyde, cis-; 4-Fluoro-1-methyl-cyclohexanecarbaldehyde; 255852-21-2; cis-4-Fluoro-1-methyl-1-cyclohexanecarboxaldehyde; 1-Cyclohexanecarboxaldehyde, 4-fluoro-1-methyl-, cis-
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxaldehyde, 4-Fluoro-1-Methyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and physical properties is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Chiral Purity (cis-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.