Description

Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3R)-Rel- (9Ci) is a chiral, fluorinated aldehyde derivative of cyclohexane, serving as a sophisticated building block in advanced organic synthesis. Its value lies in the precise stereochemistry and the introduction of fluorine, which are critical for modulating the biological activity, metabolic stability, and physical properties of target molecules. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease therapeutics.
• Agrochemical Synthesis: Used in the construction of advanced, fluorinated herbicides, fungicides, and insecticides where the fluorine atom enhances efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers where the cyclohexane backbone and fluorine impart specific thermal and chemical resistance properties.
• Flavor & Fragrance Chemistry: Potential use as an intermediate for creating complex, stereodefined aroma chemicals, leveraging the aldehyde functionality and stable ring structure.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3R)-Rel- (9Ci)
CAS No.	255852-20-1
Molecular Formula	C8H13FO
Molecular Weight	144.18 g/mol
Synonyms	(1R,3R)-3-Fluoro-1-methylcyclohexanecarbaldehyde; rel-(1R,3R)-3-Fluoro-1-methylcyclohexanecarboxaldehyde; 3-Fluoro-1-methylcyclohexanecarboxaldehyde (rel-(1R,3R)-); (1R,3R)-3-Fluoro-1-methyl-1-cyclohexanecarboxaldehyde; 255852-20-1; Fluoromethylcyclohexanecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3R)-Rel- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including chiral HPLC, GC, NMR, and MS to ensure exceptional enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and volatility. The container should be kept in a cool, dry, well-ventilated area separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.