Description

Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1S,3R)- (9Ci) is a high-purity, stereochemically defined fluorinated aldehyde building block. This compound is critical for the synthesis of complex, biologically active molecules where precise stereochemistry and fluorine substitution are required for efficacy and metabolic stability. It is primarily utilized by pharmaceutical R&D and process chemistry teams, as well as by fine chemical manufacturers specializing in advanced intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced, fluorinated agrochemicals where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers or liquid crystals with tailored properties for specialty applications.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1S,3R)- (9Ci)
CAS No.	255852-19-8
Molecular Formula	C8H13FO
Molecular Weight	144.18 g/mol
Synonyms	(1S,3R)-3-Fluoro-1-methylcyclohexanecarboxaldehyde; (1S,3R)-3-Fluoro-1-methyl-1-cyclohexanecarboxaldehyde; 3-Fluoro-1-methylcyclohexanecarboxaldehyde, (1S,3R)-; trans-3-Fluoro-1-methylcyclohexanecarboxaldehyde; (1S,3R)-rel-3-Fluoro-1-methylcyclohexanecarbaldehyde; 255852-19-8; (1S,3R)-3-Fluoro-1-methylcyclohexanecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1S,3R)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity compliant with industry standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.