Description

(R)-N4-Benzyl-2-(Benzyloxymethyl)Piperazine CAS NO 255723-98-9 is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D and fine chemical manufacturers need this material for creating enantiomerically pure drug candidates and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a ligand or catalyst component in enantioselective chemical transformations.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Peptidomimetics Development: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	(R)-N4-Benzyl-2-(Benzyloxymethyl)Piperazine
CAS No.	255723-98-9
Molecular Formula	C19H24N2O
Molecular Weight	296.41 g/mol
Synonyms	(R)-1-Benzyl-2-(benzyloxymethyl)piperazine; (R)-N-Benzyl-2-(benzyloxymethyl)piperazine; (R)-1-Benzyl-2-(phenylmethoxymethyl)piperazine; (R)-N-Bn-2-(BnOCH2)piperazine; (2R)-1-Benzyl-2-[(phenylmethoxy)methyl]piperazine; (R)-2-(Benzyloxymethyl)-N-benzylpiperazine; (R)-N4-Bn-2-BOM-Piperazine
EINECS	Contact for details

Quality Control

Our (R)-N4-Benzyl-2-(Benzyloxymethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.