Description

2-Chloro-3-(trifluoromethyl)quinoxaline is a high-value, multi-functional heterocyclic building block characterized by its halogenated and fluorinated structure. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering significant reactivity for cross-coupling and functionalization reactions. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, leveraging the biological activity of the quinoxaline core.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for OLEDs and charge-transport materials.
• Cross-Coupling Reactions: The chloro substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Fluorinated Compound Library: A valuable building block for medicinal chemistry to explore the effects of the trifluoromethyl group on pharmacokinetics.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	2-Chloro-3-(trifluoromethyl)quinoxaline
CAS No.	254732-51-9
Molecular Formula	C9H4ClF3N2
Molecular Weight	232.59 g/mol
Synonyms	2-Chloro-3-trifluoromethylquinoxaline; Quinoxaline, 2-chloro-3-(trifluoromethyl)-; 3-Trifluoromethyl-2-chloroquinoxaline; 2-Chloro-3-(trifluoromethyl)-1,4-diazanaphthalene; 254732-51-9; CTFQ
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(trifluoromethyl)quinoxaline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures you receive a reliable product for your sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.