Description

1,2-Dihenarachidoyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid featuring two C21:0 (henarachidoyl) fatty acid chains, making it a critical component for constructing advanced lipid-based delivery systems and biomimetic membranes. Its precisely defined structure is essential for researchers and formulators requiring exceptional batch-to-batch consistency and predictable biophysical behavior. This compound is primarily utilized in the pharmaceutical and biotechnology sectors for applications such as liposomal drug delivery, membrane protein research, and as a standard for analytical methods.

Application

• Liposomal Drug Formulation: A key structural lipid for creating stable, long-circulating liposomes for targeted drug delivery, particularly for chemotherapeutic and nucleic acid-based therapies.
• Biomimetic Membrane Research: Used to construct model lipid bilayers and vesicles (e.g., giant unilamellar vesicles, GUVs) for studying membrane biophysics, protein-lipid interactions, and cellular processes.
• Analytical Standard & Reference Material: Serves as a high-purity standard for lipidomics research, mass spectrometry calibration, and quality control in phospholipid analysis.
• Excipient Development: Investigated as a functional excipient in advanced parenteral formulations to enhance stability and modulate drug release profiles.
• Cell Culture & Transfection Reagents: A component in specialized lipid mixtures used for cell transfection and to create serum supplements or defined media for sensitive cell lines.

Basic Information

Product Name	1,2-Dihenarachidoyl-Sn-Glycero-3-Phosphocholine
CAS No.	253685-28-8
Molecular Formula	C52H104NO8P
Molecular Weight	902.35 g/mol
Synonyms	DHPC (C21:0); 1,2-Dihenarachidoylphosphatidylcholine; PC(21:0/21:0); 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine; 1,2-Diheneicosanoylphosphatidylcholine; Phosphatidylcholine(42:0); (2R)-2,3-Bis(henarachidoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Dihenarachidoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay by HPLC, lipid profile, and residual solvents are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (TLC)	Single spot
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.